Automatic Nevirapine concentration interpretation system using support vector regression

Automatic Nevirapine concentration interpretation system using support vector regression

Follow-up of human immunodeficiency virus (HIV) patients treated with Nevirapine (NVP) is a necessary process to evaluate the drug resistance and the HIV mutation. It is also usually tested by immunochromatographic (IC) strip test. However, it is difficult to estimate the amount of drug the patient...

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Main Authors: Sansanee Auephanwiriyakul, Ekkalak Sumonphan, Nipon Theera-Umpon, Chatchai Tayapiwatana
Format: Journal
Published: 2018
Subjects:
Computer Science
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952040069&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49891
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-498912018-09-04T04:27:23Z Automatic Nevirapine concentration interpretation system using support vector regression Sansanee Auephanwiriyakul Ekkalak Sumonphan Nipon Theera-Umpon Chatchai Tayapiwatana Computer Science Medicine Follow-up of human immunodeficiency virus (HIV) patients treated with Nevirapine (NVP) is a necessary process to evaluate the drug resistance and the HIV mutation. It is also usually tested by immunochromatographic (IC) strip test. However, it is difficult to estimate the amount of drug the patient gets by visually inspection of color. In this paper, we propose an automatic interpretation system using a commercialized optical scanner. Several IC strips can be placed at any direction as long as they are on the scanner plate. There are three steps in the system, i.e., light intensity normalization, image segmentation and NVP concentration interpretation. We utilized the Support Vector Regression to interpret the NVP concentration. From the results, we found out the performance of the system is promising and better than that of the linear and nonlinear regression. © 2011 Elsevier Ireland Ltd. 2018-09-04T04:19:48Z 2018-09-04T04:19:48Z 2011-03-01 Journal 01692607 2-s2.0-79952040069 10.1016/j.cmpb.2010.12.014 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952040069&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49891
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Computer Science
Medicine
spellingShingle Computer Science
Medicine
Sansanee Auephanwiriyakul
Ekkalak Sumonphan
Nipon Theera-Umpon
Chatchai Tayapiwatana
Automatic Nevirapine concentration interpretation system using support vector regression
description Follow-up of human immunodeficiency virus (HIV) patients treated with Nevirapine (NVP) is a necessary process to evaluate the drug resistance and the HIV mutation. It is also usually tested by immunochromatographic (IC) strip test. However, it is difficult to estimate the amount of drug the patient gets by visually inspection of color. In this paper, we propose an automatic interpretation system using a commercialized optical scanner. Several IC strips can be placed at any direction as long as they are on the scanner plate. There are three steps in the system, i.e., light intensity normalization, image segmentation and NVP concentration interpretation. We utilized the Support Vector Regression to interpret the NVP concentration. From the results, we found out the performance of the system is promising and better than that of the linear and nonlinear regression. © 2011 Elsevier Ireland Ltd.
format Journal
author Sansanee Auephanwiriyakul
Ekkalak Sumonphan
Nipon Theera-Umpon
Chatchai Tayapiwatana
author_facet Sansanee Auephanwiriyakul
Ekkalak Sumonphan
Nipon Theera-Umpon
Chatchai Tayapiwatana
author_sort Sansanee Auephanwiriyakul
title Automatic Nevirapine concentration interpretation system using support vector regression
title_short Automatic Nevirapine concentration interpretation system using support vector regression
title_full Automatic Nevirapine concentration interpretation system using support vector regression
title_fullStr Automatic Nevirapine concentration interpretation system using support vector regression
title_full_unstemmed Automatic Nevirapine concentration interpretation system using support vector regression
title_sort automatic nevirapine concentration interpretation system using support vector regression
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952040069&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49891
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