A framework of ontology-based tablet production supporting system for a drug reformulation

This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of orig...

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Bibliographic Details
Main Authors: Nopphadol Chalortham, Phuriwat Leesawat, Taneth Ruangrajitpakorn, Thepchai Supnithi
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952160638&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49894
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Institution: Chiang Mai University
Description
Summary:This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples. © 2011 The Institute of Electronics, Information and Communication Engineers.