Involvement of P2X<inf>7</inf>purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblasts

• المؤلفون الرئيسيون: P. Montreekachon, P. Chotjumlong, J. G.M. Bolscher, K. Nazmi, V. Reutrakul, S. Krisanaprakornkit
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Dentistry
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79954880573&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49898

Background and Objective: The antimicrobial peptide LL-37, derived from human neutrophils, can directly chemoattract leukocytes and up-regulate the expression of several immune-related genes in various cell types. In this study, we wanted to determine the immunoregulatory effect of LL-37 on interleu...