A phase II study of oxaliplatin with 5-FU/folinic acid and concomitant radiotherapy as a preoperative treatment in patients with locally advanced rectal cancer

• Main Authors: I. Chitapanarux, T. Chitapanarux, E. Tharavichitkul, S. Mayurasakorn, P. Siriwittayakorn, S. Yamada, V. Lorvidhaya
• Format: Journal
• Published: 2018
• Subjects: Engineering; Health Professions; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=83455220049&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49926
• Institution: Chiang Mai University

Objective: To evaluate the activity and safety of adding oxaliplatin to a standard chemoradiotherapy schema, including 5-fluorouracil (5-FU)/folinic acid (FA), in locally-advanced rectal cancer (LARC). Methods: Two cycles of oxaliplatin 130 mg/m 2 plus FA 20 mg/m 2 bolus for 5 days and 5-FU 350 mg/m...