Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy

• Main Authors: K. Kumthip, C. Pantip, P. Chusri, S. Thongsawat, A. O'Brien, K. E. Nelson, Niwat Maneekarn
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952652957&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50036
• Institution: Chiang Mai University

Several studies have reported correlation between mutations in core and NS5A proteins of hepatitis C virus (HCV) and response to interferon (IFN) therapy. In particular, mutations in NS5A protein have been shown to correlate with responsiveness to IFN treatment of HCV-1b in Japanese patients. This s...