Frequencies of IL10 SNP genotypes by multiplex PCR-SSP and their association with viral load and CD4 counts in HIV-1-infected thais

• Main Authors: Doungnapa Kingkeow, Janet M. McNicholl, Niwat Maneekarn, Jeerang Wongtrakul, Sineenart Taechareonkul, Vinai Suriyanon, Kenrad E. Nelson, Ann Duerr, Sanit Makonkawkeyoon
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79958258680&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50040
• Institution: Chiang Mai University

Background: Interleukin (IL)-10 is an immunoregulatorycytokine, levels of which can beinfluenced by single nucleotide polymorphisms(SNPs) in the promoter. Some, but not allprevious studies have shown associations ofIL10 SNPs with HIV-1 disease progression,using markers such as viral load or CD4 coun...