Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis
Purpose: To determine the feasibility of remote diagnostic screening for cytomegalovirus (CMV) retinitis among HIV patients in northern Thailand. Design: Prospective, observational cross-sectional study. Methods: One hundred eighty-two eyes from 94 consecutive patients with HIV seen in 2008 and 2009...
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th-cmuir.6653943832-501492018-09-04T04:25:17Z Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis Somsanguan Ausayakhun Alison H. Skalet Choeng Jirawison Sakarin Ausayakhun Jeremy D. Keenan Claire Khouri Khang Nguyen Partho S. Kalyani David Heiden Gary N. Holland Todd P. Margolis Medicine Purpose: To determine the feasibility of remote diagnostic screening for cytomegalovirus (CMV) retinitis among HIV patients in northern Thailand. Design: Prospective, observational cross-sectional study. Methods: One hundred eighty-two eyes from 94 consecutive patients with HIV seen in 2008 and 2009 at a tertiary university-based medical center were photographed using a digital retinal camera. Individual and composite images were uploaded to a secure web site. Three expert graders accessed the electronic images and graded each image for signs of CMV retinitis. Results of remote expert grading were compared with on-site patient examination by local expert ophthalmologists. Results: On-site ophthalmologists diagnosed CMV retinitis in 89 (48.9%) of 182 eyes. Trained ophthalmic photographers obtained digital retinal images for all 182 eyes. As compared with the on-site examinations, the sensitivity for detecting CMV retinitis by remote readers using composite retinal images ranged from 89% to 91%. The specificity for detecting CMV retinitis by remote readers ranged from 85% to 88%. Intrarater reliability was high, with each grader achieving a κ value of 0.93. Interrater reliability among the 3 graders also was high, with a κ value of 0.86. Conclusions: Remote diagnostic screening for CMV retinitis among HIV-positive patients may prove to be a valuable tool in countries where the burden of HIV exceeds the capacity of the local eye care providers to screen for ocular opportunistic infections. © 2011 Elsevier Inc. 2018-09-04T04:25:17Z 2018-09-04T04:25:17Z 2011-12-01 Journal 18791891 00029394 2-s2.0-81855167035 10.1016/j.ajo.2011.05.030 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=81855167035&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50149 |
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Medicine Somsanguan Ausayakhun Alison H. Skalet Choeng Jirawison Sakarin Ausayakhun Jeremy D. Keenan Claire Khouri Khang Nguyen Partho S. Kalyani David Heiden Gary N. Holland Todd P. Margolis Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
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Purpose: To determine the feasibility of remote diagnostic screening for cytomegalovirus (CMV) retinitis among HIV patients in northern Thailand. Design: Prospective, observational cross-sectional study. Methods: One hundred eighty-two eyes from 94 consecutive patients with HIV seen in 2008 and 2009 at a tertiary university-based medical center were photographed using a digital retinal camera. Individual and composite images were uploaded to a secure web site. Three expert graders accessed the electronic images and graded each image for signs of CMV retinitis. Results of remote expert grading were compared with on-site patient examination by local expert ophthalmologists. Results: On-site ophthalmologists diagnosed CMV retinitis in 89 (48.9%) of 182 eyes. Trained ophthalmic photographers obtained digital retinal images for all 182 eyes. As compared with the on-site examinations, the sensitivity for detecting CMV retinitis by remote readers using composite retinal images ranged from 89% to 91%. The specificity for detecting CMV retinitis by remote readers ranged from 85% to 88%. Intrarater reliability was high, with each grader achieving a κ value of 0.93. Interrater reliability among the 3 graders also was high, with a κ value of 0.86. Conclusions: Remote diagnostic screening for CMV retinitis among HIV-positive patients may prove to be a valuable tool in countries where the burden of HIV exceeds the capacity of the local eye care providers to screen for ocular opportunistic infections. © 2011 Elsevier Inc. |
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Journal |
author |
Somsanguan Ausayakhun Alison H. Skalet Choeng Jirawison Sakarin Ausayakhun Jeremy D. Keenan Claire Khouri Khang Nguyen Partho S. Kalyani David Heiden Gary N. Holland Todd P. Margolis |
author_facet |
Somsanguan Ausayakhun Alison H. Skalet Choeng Jirawison Sakarin Ausayakhun Jeremy D. Keenan Claire Khouri Khang Nguyen Partho S. Kalyani David Heiden Gary N. Holland Todd P. Margolis |
author_sort |
Somsanguan Ausayakhun |
title |
Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
title_short |
Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
title_full |
Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
title_fullStr |
Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
title_full_unstemmed |
Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
title_sort |
accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis |
publishDate |
2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=81855167035&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50149 |
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