Antibody responses to hepatitis A virus vaccination in Thai HIV-infected children with immune recovery after antiretroviral therapy

The prevalence of hepatitis A virus (HAV) protective antibody in 98 Thai HIV-infected children who achieved immune recovery after antiretroviral therapy was 12.2%. After a 2-dose HAV vaccination, 98.8% (85 of 86 children) seroconverted. The geometric mean titer was 520.95 mIU/mL. In a multivariate a...

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Bibliographic Details
Main Authors: Tavitiya Sudjaritruk, Thira Sirisanthana, Virat Sirisanthana
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79951679948&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50282
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Institution: Chiang Mai University
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Summary:The prevalence of hepatitis A virus (HAV) protective antibody in 98 Thai HIV-infected children who achieved immune recovery after antiretroviral therapy was 12.2%. After a 2-dose HAV vaccination, 98.8% (85 of 86 children) seroconverted. The geometric mean titer was 520.95 mIU/mL. In a multivariate analysis, female gender, age <12 years and higher CD4 lymphocyte count at enrollment were predicting factors for high (≥250 mIU/mL) HAV antibody response. © 2011 Lippincott Williams & Wilkins, Inc.