A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry

A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry

© 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB...

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Main Authors: Sorachai Khamsan, Saisunee Liawruangrath, Aphiwat Tcerawutkulrag, Stephen G. Pyne, Mary J. Garson, Boonsom Liawruangrath
Format: Journal
Published: 2018
Subjects:
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863444888&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50332
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-503322018-09-04T04:29:11Z A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry Sorachai Khamsan Saisunee Liawruangrath Aphiwat Tcerawutkulrag Stephen G. Pyne Mary J. Garson Boonsom Liawruangrath Pharmacology, Toxicology and Pharmaceutics © 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB and NC1-H187 cell lines with the IC50values of 2.52 and 7.47 ng mL-1, compound 2 and 3 exhibited anticancer activity against KB and NC1-HI87 cell lines wilh the IC50values of 5.73, 8.14, 2.83 and 27.30 μg mL-1, respectively. Compound 2 also showed anticancer activity against MCF-7 cell line with an IC50value of 28.17 μg mL-1. The isolates showed non-cytotoxic against Vero cells. 2018-09-04T04:29:11Z 2018-09-04T04:29:11Z 2011-01-01 Journal 13072080 2-s2.0-84863444888 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863444888&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50332
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Pharmacology, Toxicology and Pharmaceutics
spellingShingle Pharmacology, Toxicology and Pharmaceutics
Sorachai Khamsan
Saisunee Liawruangrath
Aphiwat Tcerawutkulrag
Stephen G. Pyne
Mary J. Garson
Boonsom Liawruangrath
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
description © 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB and NC1-H187 cell lines with the IC50values of 2.52 and 7.47 ng mL-1, compound 2 and 3 exhibited anticancer activity against KB and NC1-HI87 cell lines wilh the IC50values of 5.73, 8.14, 2.83 and 27.30 μg mL-1, respectively. Compound 2 also showed anticancer activity against MCF-7 cell line with an IC50value of 28.17 μg mL-1. The isolates showed non-cytotoxic against Vero cells.
format Journal
author Sorachai Khamsan
Saisunee Liawruangrath
Aphiwat Tcerawutkulrag
Stephen G. Pyne
Mary J. Garson
Boonsom Liawruangrath
author_facet Sorachai Khamsan
Saisunee Liawruangrath
Aphiwat Tcerawutkulrag
Stephen G. Pyne
Mary J. Garson
Boonsom Liawruangrath
author_sort Sorachai Khamsan
title A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
title_short A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
title_full A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
title_fullStr A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
title_full_unstemmed A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
title_sort new isoflavonc from jacaranda obtusifolia h.b.k. ssp. rhombifolia (g.f.w. meijer) gentry
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863444888&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50332
_version_ 1681423570721308672

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