Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study

Objective: This study aims to examine the efficacy of atomoxetine in treating symptoms of attention deficit hyperactivity disorder (ADHD) in children with severe autistic disorder. Method: Children with severe autistic disorder who had symptoms of ADHD were given atomoxetine for 10 weeks. The effica...

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Main Author: Chawanun Charnsil
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/50360
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spelling th-cmuir.6653943832-503602018-09-04T04:30:54Z Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study Chawanun Charnsil Psychology Objective: This study aims to examine the efficacy of atomoxetine in treating symptoms of attention deficit hyperactivity disorder (ADHD) in children with severe autistic disorder. Method: Children with severe autistic disorder who had symptoms of ADHD were given atomoxetine for 10 weeks. The efficacy of atomoxetine was evaluated by using the Aberrant Behavior Checklist (ABC) to rate ADHD symptoms at baseline, week 6, and week 10. The Clinical Global Impression-Improvement (CGI-I) scale was used as secondary outcome to assess the overall improvement of the children's development at week 10. Results: A total of 12 children participated in this study. Although CGI-I scores showed improvement at week 10, the ABC hyperactivity subscale did not show a significant improvement of the ADHD symptoms at baseline (M = 33.89) compared to those at week 10 (M = 31.78, p = .62). Conclusion: Atomoxetine did not benefit children with severe autistic disorder who have ADHD symptoms. © 2011 SAGE Publications. 2018-09-04T04:30:54Z 2018-09-04T04:30:54Z 2011-11-01 Journal 15571246 10870547 2-s2.0-82455167368 10.1177/1087054710376907 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=82455167368&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50360
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Psychology
spellingShingle Psychology
Chawanun Charnsil
Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
description Objective: This study aims to examine the efficacy of atomoxetine in treating symptoms of attention deficit hyperactivity disorder (ADHD) in children with severe autistic disorder. Method: Children with severe autistic disorder who had symptoms of ADHD were given atomoxetine for 10 weeks. The efficacy of atomoxetine was evaluated by using the Aberrant Behavior Checklist (ABC) to rate ADHD symptoms at baseline, week 6, and week 10. The Clinical Global Impression-Improvement (CGI-I) scale was used as secondary outcome to assess the overall improvement of the children's development at week 10. Results: A total of 12 children participated in this study. Although CGI-I scores showed improvement at week 10, the ABC hyperactivity subscale did not show a significant improvement of the ADHD symptoms at baseline (M = 33.89) compared to those at week 10 (M = 31.78, p = .62). Conclusion: Atomoxetine did not benefit children with severe autistic disorder who have ADHD symptoms. © 2011 SAGE Publications.
format Journal
author Chawanun Charnsil
author_facet Chawanun Charnsil
author_sort Chawanun Charnsil
title Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
title_short Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
title_full Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
title_fullStr Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
title_full_unstemmed Efficacy of atomoxetine in children with severe autistic disorders and symptoms of ADHD: An open-label study
title_sort efficacy of atomoxetine in children with severe autistic disorders and symptoms of adhd: an open-label study
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=82455167368&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50360
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