Role of SHIP-1 in the adaptive immune responses to aeroallergen in the airway

• Main Authors: Sukit Roongapinun, Sun Young Oh, Fan Wu, Ampai Panthong, Tao Zheng, Zhou Zhu
• Format: Journal
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78649789126&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50405
• Institution: Chiang Mai University

Background: Th2-dominated inflammatory response in the airway is an integral component in the pathogenesis of allergic asthma. Accumulating evidence supports the notion that the phosphoinositide 3-kinase (PI3K) pathway is involved in the process. We previously reported that SHIP-1, a negative regula...