Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H 2O 2 sca...
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th-cmuir.6653943832-504652018-09-04T04:52:42Z Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract Supawatchara Singhatong Donrawee Leelarungrayub Chaiyavat Chaiyasut Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H 2O 2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H 2O 2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect. 2018-09-04T04:41:19Z 2018-09-04T04:41:19Z 2010-05-18 Journal 19960875 19960875 2-s2.0-77954054479 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954054479&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50465 |
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Agricultural and Biological Sciences Medicine Pharmacology, Toxicology and Pharmaceutics Supawatchara Singhatong Donrawee Leelarungrayub Chaiyavat Chaiyasut Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
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The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H 2O 2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H 2O 2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect. |
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Supawatchara Singhatong Donrawee Leelarungrayub Chaiyavat Chaiyasut |
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Supawatchara Singhatong Donrawee Leelarungrayub Chaiyavat Chaiyasut |
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Supawatchara Singhatong |
title |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_short |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_full |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_fullStr |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_full_unstemmed |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_sort |
antioxidant and toxicity activities of artocarpus lakoocha roxb. heartwood extract |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954054479&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50465 |
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