Baculovirus display of single chain antibody (scFv) using a novel signal peptide

• Main Authors: Kuntida Kitidee, Sawitree Nangola, Gaëlle Gonzalez, Pierre Boulanger, Chatchai Tayapiwatana, Saw See Hong
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78349298326&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50528
• Institution: Chiang Mai University

Background: Cells permissive to virus can become refractory to viral replication upon intracellular expression of single chain fragment variable (scFv) antibodies directed towards viral structural or regulatory proteins, or virus-coded enzymes. For example, an intrabody derived from MH-SVM33, a mono...