Novel ferrocenic steroidal drug derivatives and their bioactivities

• Main Authors: Jiradej Manosroi, Kanjana Rueanto, Korawinwich Boonpisuttinant, Worapaka Manosroi, Christophe Biot, Hiroyuki Akazawa, Toshihiro Akihisa, Witchapong Issarangporn, Aranya Manosroi
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952734111&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50570
• Institution: Chiang Mai University

Seven novel ferrocenic derivatives, compounds 1-7, were synthesized from steroidal drugs by Aldol condensation reaction. The derivatives were purified by chromatography, and their structures were determined on the basis of HR-ESI-MS and two-dimensional NMR spectroscopy. The purity of all derivatives...