Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789

Six new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4α-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789. Compound 7 showed anti-HSV-1 activity...

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Main Authors:	Taridaporn Bunyapaiboonsri, Seangaroon Yoiprommarat, Prasert Srikitikulchai, Kitlada Srichomthong, Saisamorn Lumyong
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76049090657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50601
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-50601
record_format	dspace
spelling	th-cmuir.6653943832-506012018-09-04T04:52:47Z Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789 Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Six new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4α-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789. Compound 7 showed anti-HSV-1 activity (IC50 ) 14 μM) and cytotoxic activities against KB, BC, NCI-H187, and nonmalignant (Vero) cell lines with respective IC50 values of 37, 26, 32, and 60 μM. Cytotoxic activity against the BC cell line was also observed for compound 6, with an IC50 value of 48 μM. © 2010 American Chemical Society and American Society of Pharmacognosy. 2018-09-04T04:42:48Z 2018-09-04T04:42:48Z 2010-01-22 Journal 01633864 2-s2.0-76049090657 10.1021/np900650c https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76049090657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50601
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
description	Six new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4α-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789. Compound 7 showed anti-HSV-1 activity (IC50 ) 14 μM) and cytotoxic activities against KB, BC, NCI-H187, and nonmalignant (Vero) cell lines with respective IC50 values of 37, 26, 32, and 60 μM. Cytotoxic activity against the BC cell line was also observed for compound 6, with an IC50 value of 48 μM. © 2010 American Chemical Society and American Society of Pharmacognosy.
format	Journal
author	Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong
author_facet	Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong
author_sort	Taridaporn Bunyapaiboonsri
title	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
title_short	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
title_full	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
title_fullStr	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
title_full_unstemmed	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
title_sort	oblongolides from the endophytic fungus phomopsis sp. bcc 9789
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76049090657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50601
_version_	1681423619157131264

Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789

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