Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells

• Main Authors: Fahsai Kantawong, Karl E.V. Burgess, Kamburapola Jayawardena, Andrew Hart, Mathis O. Riehle, Richard O. Oreffo, Matthew J. Dalby, Richard Burchmore
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Engineering; Materials Science
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77956752542&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50620
• Institution: Chiang Mai University

Human skeletal stem cells (STRO-1 positive/STRO-1+) respond to different topographical features in various ways. On a flat surface these cells spread and tend to develop a fibroblast-like morphology. On a microgrooved surface enriched skeletal stem cell populations prefer to stretch along the groove...