Entrapment enhancement of peptide drugs in niosomes

• Main Authors: Aranya Manosroi, Penpan Khanrin, Rolf G. Werner, Friedrich Gtz, Worapaka Manosroi, Jiradej Manosroi
• Format: Journal
• Published: 2018
• Subjects: Chemical Engineering; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951455054&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50643
• Institution: Chiang Mai University

The objective of this study was to enhance the entrapment of various charged peptide drugs [(bacitracin (BCT), insulin and bovine serum albumin (BSA)] in niosomes by modifying the vesicular charge compositions. Cationic, anionic and neutral niosomes were prepared from sorbitan monostearate (Span 60)...