Amido-3-hydroxypyridin-4-ones as iron(III) ligands

The synthesis and physicochemical properties of a range of 2and 6-amido-3-hydroxypyridin-4-ones are described. All the amido-substituted 3-hydroxypyridin-4-ones have lower pKavalues than 1,2-dimethyl-3-hydr-oxypyridin-4-one (deferiprone). This is due to the inductive effect of the amido group. Furth...

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Bibliographic Details
Main Authors: Sirivipa Piyamongkol, Yong M. Ma, Xiao L. Kong, Zu D. Liu, Mutlu D. Aytemir, Dick Van Der Helm, Robert C. Hider
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952734302&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50671
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Institution: Chiang Mai University