Amido-3-hydroxypyridin-4-ones as iron(III) ligands

• المؤلفون الرئيسيون: Sirivipa Piyamongkol, Yong M. Ma, Xiao L. Kong, Zu D. Liu, Mutlu D. Aytemir, Dick Van Der Helm, Robert C. Hider
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Chemistry
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952734302&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50671

The synthesis and physicochemical properties of a range of 2and 6-amido-3-hydroxypyridin-4-ones are described. All the amido-substituted 3-hydroxypyridin-4-ones have lower pKavalues than 1,2-dimethyl-3-hydr-oxypyridin-4-one (deferiprone). This is due to the inductive effect of the amido group. Furth...