Application of factor analysis on Mycobacterium tuberculosis transcriptional responses for drug clustering, drug target, and pathway detections

• Main Authors: Chaijaruwanich J., Khamphachua J., Prasitwattanaseree S., Warit S., Palittapongarnpim P.
• Format: Conference or Workshop Item
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-33749377703&partnerID=40&md5=d74fa678e9786cae4ee60128159af89a; http://cmuir.cmu.ac.th/handle/6653943832/5068
• Institution: Chiang Mai University

Recently, the differential transcriptional responses of Mycobacterium tuberculosis to drug and growth-inhibitory conditions were monitored to generate a data set of 436 microarray profiles. These profiles were valuably used for grouping drugs, identifying drug targets and detecting related pathways,...