Impact of HIV/aids on child mortality before the highly active antiretroviral therapy era: A study in Pointe-Noire, Republic of Congo

• Main Authors: Sophie Le Coeur, Camille Lallemant, Gaston Halembokaka, Gaelle Baty, Nicole Ngo-Giang-Huong, Francis Barin
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77956832003&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50920
• Institution: Chiang Mai University

Few studies have documented the contribution of HIV/AIDS to mortality among children under 15 years. From June 30 to October 19, 2001, all child deaths (n=588) registered to the morgue and/or hospitals of the city of Pointe-Noire, Congo, were investigated using a combined approach including an interview of relatives and postmortem clinical and biological HIV diagnosis. Twenty-one percent of children were HIV positive, while 10.5 of deaths were attributed to AIDS. The most common causes of death in HIV-infected children were pneumonia (30), pyrexia (22), diarrhoea (16) and wasting syndrome (16). Infant mortality rate was estimated 6.3 times higher in children born to HIV-infected mothers compared to HIV-uninfected mothers. This study provides a direct measure of HIV/AIDS as impact on child mortality using a rapid and reliable method. A significant number of deaths could be prevented if HIV infection was diagnosed earlier and infants were provided with antiretroviral treatments. Copyright © 2010 Camille Lallemant et al.