Pharmacokinetics and virologic response of zidovudine/lopinavir/ritonavir initiated during the third trimester of pregnancy

• Main Authors: Tim R. Cressey, Gonzague Jourdain, Boonsong Rawangban, Supang Varadisai, Rucha Kongpanichkul, Prapan Sabsanong, Prapap Yuthavisuthi, Somnuk Chirayus, Nicole Ngo-Giang-Huong, Nipunporn Voramongkol, Somsak Pattarakulwanich, Marc Lallemant
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77956232308&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50921
• Institution: Chiang Mai University

Objective: To evaluate the pharmacokinetics and HIV viral load response following initiation during the third trimester of pregnancy of zidovudine plus standard-dose lopinavir boosted with ritonavir (LPV/r), twice daily, until delivery for the prevention of mother-to-child transmission of HIV. Desig...