Venous Doppler studies in low-output and high-output hydrops fetalis

Objective: The objective of the study was to compare fetal venous Doppler flow reflecting cardiac function in fetuses with hydrops fetalis between a group of congenital heart defect (low cardiac output) and a fetal anemia group (high cardiac output). Study Design: This was a prospective cross-sectio...

Full description

Saved in:
Bibliographic Details
Main Authors: Theera Tongsong, Fuanglada Tongprasert, Kasemsri Srisupundit, Suchaya Luewan
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78149281389&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51027
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-51027
record_format dspace
spelling th-cmuir.6653943832-510272018-09-04T04:50:21Z Venous Doppler studies in low-output and high-output hydrops fetalis Theera Tongsong Fuanglada Tongprasert Kasemsri Srisupundit Suchaya Luewan Medicine Objective: The objective of the study was to compare fetal venous Doppler flow reflecting cardiac function in fetuses with hydrops fetalis between a group of congenital heart defect (low cardiac output) and a fetal anemia group (high cardiac output). Study Design: This was a prospective cross-sectional analysis. It was conducted at the Maharaj Nakorn Chiang Mai Hospital, Tertiary center, Medical School. The study included fetuses with hydrops fetalis secondary to cardiac causes (low output group) and anemia (high output group). All fetuses underwent ultrasound examination to assess ductus venosus (DV) and umbilical vein (UV) Doppler indices. The results were related to normal reference range and were also compared between the group of high-output and the low-output group. Results: Sixty-nine hydropic fetuses were available for analysis, 50 in the high-output group and 19 in the low-output group. The peak velocity index, preload index, and the pulsatility index of the DV were significantly low in the high-output group, whereas they were significantly high in the low-output group. The umbilical vein pulsations were found in 78.9% of the fetuses with low-output hydrops fetalis but only 28.0% of fetuses in the high output group (P < .001). Conclusion: New insights gained from this study are that hydrops caused by severe anemia because of hemoglobin Bart's is not associated with high central venous pressures as is seen in hydropic fetuses with coronary heart disease. This suggests that cardiac decompensation is not the primary mechanism of hydrops in these anemic fetuses. Additionally, umbilical vein pulsations are not a sign of cardiac failure in the anemic group. © 2010 Mosby, Inc. 2018-09-04T04:50:21Z 2018-09-04T04:50:21Z 2010-11-01 Journal 00029378 2-s2.0-78149281389 10.1016/j.ajog.2010.06.003 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78149281389&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51027
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Theera Tongsong
Fuanglada Tongprasert
Kasemsri Srisupundit
Suchaya Luewan
Venous Doppler studies in low-output and high-output hydrops fetalis
description Objective: The objective of the study was to compare fetal venous Doppler flow reflecting cardiac function in fetuses with hydrops fetalis between a group of congenital heart defect (low cardiac output) and a fetal anemia group (high cardiac output). Study Design: This was a prospective cross-sectional analysis. It was conducted at the Maharaj Nakorn Chiang Mai Hospital, Tertiary center, Medical School. The study included fetuses with hydrops fetalis secondary to cardiac causes (low output group) and anemia (high output group). All fetuses underwent ultrasound examination to assess ductus venosus (DV) and umbilical vein (UV) Doppler indices. The results were related to normal reference range and were also compared between the group of high-output and the low-output group. Results: Sixty-nine hydropic fetuses were available for analysis, 50 in the high-output group and 19 in the low-output group. The peak velocity index, preload index, and the pulsatility index of the DV were significantly low in the high-output group, whereas they were significantly high in the low-output group. The umbilical vein pulsations were found in 78.9% of the fetuses with low-output hydrops fetalis but only 28.0% of fetuses in the high output group (P < .001). Conclusion: New insights gained from this study are that hydrops caused by severe anemia because of hemoglobin Bart's is not associated with high central venous pressures as is seen in hydropic fetuses with coronary heart disease. This suggests that cardiac decompensation is not the primary mechanism of hydrops in these anemic fetuses. Additionally, umbilical vein pulsations are not a sign of cardiac failure in the anemic group. © 2010 Mosby, Inc.
format Journal
author Theera Tongsong
Fuanglada Tongprasert
Kasemsri Srisupundit
Suchaya Luewan
author_facet Theera Tongsong
Fuanglada Tongprasert
Kasemsri Srisupundit
Suchaya Luewan
author_sort Theera Tongsong
title Venous Doppler studies in low-output and high-output hydrops fetalis
title_short Venous Doppler studies in low-output and high-output hydrops fetalis
title_full Venous Doppler studies in low-output and high-output hydrops fetalis
title_fullStr Venous Doppler studies in low-output and high-output hydrops fetalis
title_full_unstemmed Venous Doppler studies in low-output and high-output hydrops fetalis
title_sort venous doppler studies in low-output and high-output hydrops fetalis
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78149281389&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51027
_version_ 1681423695642361856