Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery
Objective: To compare the efficacy and effectiveness between ULTRACETTM, a new analgesic combination of tramadol/ acetaminophen, and tramadol/acetaminophen for acute postoperative pain after upper extremity surgery. Study design: A double blind randomized controlled trial. Material and Method: One h...
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th-cmuir.6653943832-510532018-09-04T04:50:51Z Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery Passakorn Sawaddiruk Sahattaya Paiboonworachat Kittichai Janthawichai Medicine Objective: To compare the efficacy and effectiveness between ULTRACETTM, a new analgesic combination of tramadol/ acetaminophen, and tramadol/acetaminophen for acute postoperative pain after upper extremity surgery. Study design: A double blind randomized controlled trial. Material and Method: One hundred and eighty patients who underwent upper extremity surgery under brachial plexus block were randomized to receive either ULTRACETTM (n = 87) or tramadol and acetaminophen (n = 93) immediately after surgery in the postanesthetic care unit (PACU). Total morphine requirement, pain score (VRS) and drug adverse effects were compared between those two groups using independent single t-test, Mann-Whitney U-test, Chi-square test and Fisher-exact test respectively. Results: Total morphine requirement was significantly lower in subjects who used ULTRACETTM when compared with the tramadol and acetaminophen group (0.51 and 0.69 mg in the first 6 hours after the operation, 0.0 and 0.13 mg in hours 6-12 after the operation). Moreover, there were fewer side effects in this ULTRACETTM group too. Conclusion: ULTRACETTM has more efficacy and fewer side effects when compared with tramadol and acetaminophen in acute postoperative pain surgery. 2018-09-04T04:50:51Z 2018-09-04T04:50:51Z 2010-07-01 Journal 01252208 01252208 2-s2.0-77955071147 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77955071147&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51053 |
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Medicine Passakorn Sawaddiruk Sahattaya Paiboonworachat Kittichai Janthawichai Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
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Objective: To compare the efficacy and effectiveness between ULTRACETTM, a new analgesic combination of tramadol/ acetaminophen, and tramadol/acetaminophen for acute postoperative pain after upper extremity surgery. Study design: A double blind randomized controlled trial. Material and Method: One hundred and eighty patients who underwent upper extremity surgery under brachial plexus block were randomized to receive either ULTRACETTM (n = 87) or tramadol and acetaminophen (n = 93) immediately after surgery in the postanesthetic care unit (PACU). Total morphine requirement, pain score (VRS) and drug adverse effects were compared between those two groups using independent single t-test, Mann-Whitney U-test, Chi-square test and Fisher-exact test respectively. Results: Total morphine requirement was significantly lower in subjects who used ULTRACETTM when compared with the tramadol and acetaminophen group (0.51 and 0.69 mg in the first 6 hours after the operation, 0.0 and 0.13 mg in hours 6-12 after the operation). Moreover, there were fewer side effects in this ULTRACETTM group too. Conclusion: ULTRACETTM has more efficacy and fewer side effects when compared with tramadol and acetaminophen in acute postoperative pain surgery. |
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Passakorn Sawaddiruk Sahattaya Paiboonworachat Kittichai Janthawichai |
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Passakorn Sawaddiruk Sahattaya Paiboonworachat Kittichai Janthawichai |
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Passakorn Sawaddiruk |
title |
Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
title_short |
Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
title_full |
Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
title_fullStr |
Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
title_full_unstemmed |
Comparison of efficacy and effectiveness between ULTRACETTM and Tramadol/Acetaminophen in acute postoperative pain after upper extremity surgery |
title_sort |
comparison of efficacy and effectiveness between ultracettm and tramadol/acetaminophen in acute postoperative pain after upper extremity surgery |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77955071147&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51053 |
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