Association between detection of HIV-1 DNA resistance mutations by a sensitive assay at initiation of antiretroviral therapy and virologic failure

• Main Authors: Gonzague Jourdain, Thor Andrew Wagner, Nicole Ngo-Giang-Huong, Wasna Sirirungsi, Virat Klinbuayaem, Federica Fregonese, Issaren Nantasen, Malee Techapornroong, Guttiga Halue, Ampaipith Nilmanat, Pakorn Wittayapraparat, Veeradet Chalermpolprapa, Panita Pathipvanich, Prapap Yuthavisuthi, Lisa M. Frenkel, Marc Lallemant
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951790626&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51071
• Institution: Chiang Mai University

Background. Antiretroviral therapy (ART) has become more available throughout the developing world during the past 5 years. The World Health Organization recommends nonnucleoside reverse-transcriptase inhibitor-based regimens as initial ART. However, their efficacy may be compromised by resistance m...