Splenic artery: Peak systolic velocity of normal fetuses

Objective To establish a reference range of splenic artery peak systolic velocity 1(SpA-PSV) in the normal singleton pregnancies (14-40 weeks). Methods A prospective descriptive study was conducted on uncomplicated singleton pregnancies with normal fetuses and accurate gestational age were recruited...

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Bibliographic Details
Main Authors: Theera Tongsong, Fuanglada Tongprasert, Kasemsri Srisupundit, Suchaya Luewan
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950628241&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51076
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Institution: Chiang Mai University
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Summary:Objective To establish a reference range of splenic artery peak systolic velocity 1(SpA-PSV) in the normal singleton pregnancies (14-40 weeks). Methods A prospective descriptive study was conducted on uncomplicated singleton pregnancies with normal fetuses and accurate gestational age were recruited into the study. The Doppler measurements of SpA-PSV were performed by the experienced sonographers with the high-resolution machine (Aloka Prosound alpha-10, Tokyo, Japan, or Voluson E8, GE Healthcare, USA). Results A total of 540 measurements were performed, ranging from 15 to 30 for each gestational week (GA). The best regression model between GA and SpA-PSV was observed to be linear function with an equation as follows: SpA-PSV (cm/s) = -1.433 +1.186 (GA, weeks) (r2 = 0.573). The table of nomogram for various percentile ranges was constructed. The results show a continuous increase in SpA-PSV over the period from 14 to 40 weeks. Conclusion A nomogram for SpA-PSV for each GA during 14-40 weeks was constructed. This reference range may be a useful non-invasive tool in risk assessment for fetal anemia, especially due to homozygous alpha-thalasse-mia-1 or fetal isoimmunization.