Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer

The objective of this study was to evaluate the outcome, prognostic factors and complications of early stage cervical cancer patients treated with radical hysterectomy and pelvic lymphadenectomy (RHPL). The medical records of cervical cancer patients undergoing RHPL at Chiang Mai University Hospital...

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Main Authors: P. Suprasert, J. Srisomboon, K. Charoenkwan, S. Siriaree, C. Cheewakriangkrai, C. Kietpeerakool, C. Phongnarisorn, J. Sae-Teng
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Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/51083
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spelling th-cmuir.6653943832-510832018-09-04T04:51:20Z Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer P. Suprasert J. Srisomboon K. Charoenkwan S. Siriaree C. Cheewakriangkrai C. Kietpeerakool C. Phongnarisorn J. Sae-Teng Medicine The objective of this study was to evaluate the outcome, prognostic factors and complications of early stage cervical cancer patients treated with radical hysterectomy and pelvic lymphadenectomy (RHPL). The medical records of cervical cancer patients undergoing RHPL at Chiang Mai University Hospital over 12 years, between January 1995 and December 2006 were reviewed. There were 1,253 patients in the study period. The mean age was 44 years of age. Of these, 26.9 had prior diagnostic conisation. The maximum tumour size was 8cm. The most common histology was squamous cell carcinoma (67) followed by adenocarcinoma (23). The distribution of FIGO staging was: stage IA 8.7; stage IB 15.8; stage IB1 61; stage IB2 6.2; and stage IIA 8.5. Pelvic nodes, parametrial and vaginal margin involvement were detected in 15.9, 10.7 and 3.8 of the patients, respectively. A total of 66.5 of patients underwent RHPL without adjuvant treatment; 12.1 received neoadjuvant chemotherapy. The estimated 10-year recurrence-free survival rate was 90. Stage IB2/IIA, non-squamous cell carcinoma, nodal involvement and positive vaginal margins were independent, significant, poor prognostic factors. The most common long-term complication was lymphoedema. It was concluded that early stage cervical cancer patients treated with RHPL have long-term favourable outcome with minimal morbidity. Stage IB2 and IIA, non-squamous cell carcinoma, nodal and vaginal involvement were independent adverse prognostic factors. © 2010 Informa Healthcare USA, Inc. 2018-09-04T04:51:20Z 2018-09-04T04:51:20Z 2010-04-01 Journal 13646893 01443615 2-s2.0-77950815437 10.3109/01443610903585192 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950815437&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51083
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
P. Suprasert
J. Srisomboon
K. Charoenkwan
S. Siriaree
C. Cheewakriangkrai
C. Kietpeerakool
C. Phongnarisorn
J. Sae-Teng
Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
description The objective of this study was to evaluate the outcome, prognostic factors and complications of early stage cervical cancer patients treated with radical hysterectomy and pelvic lymphadenectomy (RHPL). The medical records of cervical cancer patients undergoing RHPL at Chiang Mai University Hospital over 12 years, between January 1995 and December 2006 were reviewed. There were 1,253 patients in the study period. The mean age was 44 years of age. Of these, 26.9 had prior diagnostic conisation. The maximum tumour size was 8cm. The most common histology was squamous cell carcinoma (67) followed by adenocarcinoma (23). The distribution of FIGO staging was: stage IA 8.7; stage IB 15.8; stage IB1 61; stage IB2 6.2; and stage IIA 8.5. Pelvic nodes, parametrial and vaginal margin involvement were detected in 15.9, 10.7 and 3.8 of the patients, respectively. A total of 66.5 of patients underwent RHPL without adjuvant treatment; 12.1 received neoadjuvant chemotherapy. The estimated 10-year recurrence-free survival rate was 90. Stage IB2/IIA, non-squamous cell carcinoma, nodal involvement and positive vaginal margins were independent, significant, poor prognostic factors. The most common long-term complication was lymphoedema. It was concluded that early stage cervical cancer patients treated with RHPL have long-term favourable outcome with minimal morbidity. Stage IB2 and IIA, non-squamous cell carcinoma, nodal and vaginal involvement were independent adverse prognostic factors. © 2010 Informa Healthcare USA, Inc.
format Journal
author P. Suprasert
J. Srisomboon
K. Charoenkwan
S. Siriaree
C. Cheewakriangkrai
C. Kietpeerakool
C. Phongnarisorn
J. Sae-Teng
author_facet P. Suprasert
J. Srisomboon
K. Charoenkwan
S. Siriaree
C. Cheewakriangkrai
C. Kietpeerakool
C. Phongnarisorn
J. Sae-Teng
author_sort P. Suprasert
title Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
title_short Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
title_full Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
title_fullStr Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
title_full_unstemmed Twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
title_sort twelve years experience with radical hysterectomy and pelvic lymphadenectomy in early stage cervical cancer
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950815437&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51083
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