Sex difference in composition of plaques of patients undergoing carotid endarterectomy
Our study aimed to examine the hypothesis that women have more stable plaques (a lower proportion of lipid component and a higher proportion of fibrous tissue) compared to men. Plaque specimens of 141 consecutive carotid endarterectomy patients (60 females and 81 males) were studied. Medical histori...
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th-cmuir.6653943832-510892018-09-04T04:51:26Z Sex difference in composition of plaques of patients undergoing carotid endarterectomy Kittipan Rerkasem Patrick J. Gallagher Robert F. Grimble Philip C. Calder Clifford P. Shearman Medicine Our study aimed to examine the hypothesis that women have more stable plaques (a lower proportion of lipid component and a higher proportion of fibrous tissue) compared to men. Plaque specimens of 141 consecutive carotid endarterectomy patients (60 females and 81 males) were studied. Medical histories were recorded and the plasma concentrations of cholesterol and inflammatory markers were measured. We found that plaques from females had significantly less lipid than those from males (p = .01): the mean percentage of plaque lipid for women and men was 47.8% and 58.2%, respectively. Plaques from females had more fibrous tissue than those from men (p = .02): the mean percentage of fibrous tissue for women and men was 38.8% and 29.8%, respectively. This study concluded that the histology of carotid artery plaques from women appears to be more stable than that of those from men. © BC Decker Inc. All rights reserved. 2018-09-04T04:51:26Z 2018-09-04T04:51:26Z 2010-04-01 Journal 17085381 2-s2.0-77950809151 10.2310/6670.2010.00008 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950809151&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51089 |
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Medicine Kittipan Rerkasem Patrick J. Gallagher Robert F. Grimble Philip C. Calder Clifford P. Shearman Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
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Our study aimed to examine the hypothesis that women have more stable plaques (a lower proportion of lipid component and a higher proportion of fibrous tissue) compared to men. Plaque specimens of 141 consecutive carotid endarterectomy patients (60 females and 81 males) were studied. Medical histories were recorded and the plasma concentrations of cholesterol and inflammatory markers were measured. We found that plaques from females had significantly less lipid than those from males (p = .01): the mean percentage of plaque lipid for women and men was 47.8% and 58.2%, respectively. Plaques from females had more fibrous tissue than those from men (p = .02): the mean percentage of fibrous tissue for women and men was 38.8% and 29.8%, respectively. This study concluded that the histology of carotid artery plaques from women appears to be more stable than that of those from men. © BC Decker Inc. All rights reserved. |
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Journal |
author |
Kittipan Rerkasem Patrick J. Gallagher Robert F. Grimble Philip C. Calder Clifford P. Shearman |
author_facet |
Kittipan Rerkasem Patrick J. Gallagher Robert F. Grimble Philip C. Calder Clifford P. Shearman |
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Kittipan Rerkasem |
title |
Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
title_short |
Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
title_full |
Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
title_fullStr |
Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
title_full_unstemmed |
Sex difference in composition of plaques of patients undergoing carotid endarterectomy |
title_sort |
sex difference in composition of plaques of patients undergoing carotid endarterectomy |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950809151&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51089 |
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