Monitoring and impact of fluconazole serum and cerebrospinal fluid concentration in HIV-associated cryptococcal meningitis-infected patients

• Main Authors: W. Manosuthi, P. Chetchotisakd, T. L. Nolen, D. Wallace, S. Sungkanuparph, T. Anekthananon, K. Supparatpinyo, P. G. Pappas, R. A. Larsen, S. G. Filler, D. Andes
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950813660&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51091
• Institution: Chiang Mai University

Objectives:The aim of the present study was to assess fluconazole pharmacokinetic measures in serum and cerebrospinal fluid (CSF); and the correlation of these measures with clinical outcomes of invasive fungal infections. Methods:A randomized trial was conducted in HIV-infected patients receiving t...