Immature oocytes in "apparent empty follicle syndrome": A case report

Empty follicle syndrome (EFS) is a condition in which no oocytes are obtained after an apparently successful ovarian stimulation. Genuine EFS (GEFS) is differentiated from false EFS by an optimal level of human chorionic gonadotropin on the day of oocyte retrieval. Some believe that GEFS does not ex...

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Main Authors: Teraporn Vutyavanich, Waraporn Piromlertamorn, Jason Ellis
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/51127
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spelling th-cmuir.6653943832-511272018-09-04T04:52:00Z Immature oocytes in "apparent empty follicle syndrome": A case report Teraporn Vutyavanich Waraporn Piromlertamorn Jason Ellis Medicine Empty follicle syndrome (EFS) is a condition in which no oocytes are obtained after an apparently successful ovarian stimulation. Genuine EFS (GEFS) is differentiated from false EFS by an optimal level of human chorionic gonadotropin on the day of oocyte retrieval. Some believe that GEFS does not exist and that it is only a reflection of the margin of error attendant upon the procedure of oocyte aspiration. Others believe that GEFS is caused by dysfunctional folliculogenesis, resulting in early atresia of oocytes. In this report, we present a case of apparent GEFS, in which immature oocytes were identified after filtration of follicular aspirates. Our findings suggest that delayed maturation of oocyte cumulus complexes in response to HCG might be an etiologic mechanism in some cases of GEFS. This creates a situation similar to the aspiration of immature follicles, where germinal vesicle-stage oocytes with dense scanty cumulus cells are often difficult to identify under a dissecting microscope. Copyright © 2010 Teraporn Vutyavanich et al. 2018-09-04T04:52:00Z 2018-09-04T04:52:00Z 2010-01-01 Journal 16879635 16879627 2-s2.0-84895069737 10.1155/2010/367505 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84895069737&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51127
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Teraporn Vutyavanich
Waraporn Piromlertamorn
Jason Ellis
Immature oocytes in "apparent empty follicle syndrome": A case report
description Empty follicle syndrome (EFS) is a condition in which no oocytes are obtained after an apparently successful ovarian stimulation. Genuine EFS (GEFS) is differentiated from false EFS by an optimal level of human chorionic gonadotropin on the day of oocyte retrieval. Some believe that GEFS does not exist and that it is only a reflection of the margin of error attendant upon the procedure of oocyte aspiration. Others believe that GEFS is caused by dysfunctional folliculogenesis, resulting in early atresia of oocytes. In this report, we present a case of apparent GEFS, in which immature oocytes were identified after filtration of follicular aspirates. Our findings suggest that delayed maturation of oocyte cumulus complexes in response to HCG might be an etiologic mechanism in some cases of GEFS. This creates a situation similar to the aspiration of immature follicles, where germinal vesicle-stage oocytes with dense scanty cumulus cells are often difficult to identify under a dissecting microscope. Copyright © 2010 Teraporn Vutyavanich et al.
format Journal
author Teraporn Vutyavanich
Waraporn Piromlertamorn
Jason Ellis
author_facet Teraporn Vutyavanich
Waraporn Piromlertamorn
Jason Ellis
author_sort Teraporn Vutyavanich
title Immature oocytes in "apparent empty follicle syndrome": A case report
title_short Immature oocytes in "apparent empty follicle syndrome": A case report
title_full Immature oocytes in "apparent empty follicle syndrome": A case report
title_fullStr Immature oocytes in "apparent empty follicle syndrome": A case report
title_full_unstemmed Immature oocytes in "apparent empty follicle syndrome": A case report
title_sort immature oocytes in "apparent empty follicle syndrome": a case report
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84895069737&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51127
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