Effects of green tea on iron accumulation and oxidative stress in livers of iron-challenged thalassemic mice

• Main Authors: T. Saewong, S. Ounjaijean, Y. Mundee, K. Pattanapanyasat, S. Fucharoen, J. B. Porter, S. Srichairatanakool
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77953510012&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51151
• Institution: Chiang Mai University

Liver is affected by secondary iron overload in transfusions dependent β-thalassemia patients. The redox iron can generate reactive oxidants that damage biomolecules, leading to liver fibrosis and cirrhosis. Iron chelators are used to treat thalassemias to achieve negative iron balance and relieve o...