Enhancement of transdermal absorption, gene expression and stability of tyrosinase plasmid (pMEL34)-loaded elastic cationic niosomes: Potential application in vitiligo treatment

• المؤلفون الرئيسيون: Jiradej Manosroi, Narinthorn Khositsuntiwong, Worapaka Manosroi, Friedrich Götz, Rolf G. Werner, Aranya Manosroi
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77955109408&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51158

The pMEL34 was loaded in elastic cationic niosomes (Tween61/Cholesterol/ DDAB at 1:1:0.5 molar ratio) by chloroform film method with sonication and rehydrated with 25% ethanol. The amount of pMEL34 was determined by gel electrophoresis and gel documentation. The maximum loading of pMEL34 in elastic...