Potent Melanin Production Enhancement of Human Tyrosinase Gene by Tat and an Entrapment in Elastic Cationic Niosomes: Potential Application in Vitiligo Gene Therapy

• Main Authors: Jiradej Manosroi, Narinthorn Khositsuntiwong, Friedrich Götz, Rolf G. Werner, Worapaka Manosroi, Aranya Manosroi
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868106277&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51332
• Institution: Chiang Mai University

Potent melanin production enhancement of human tyrosinase plasmid (pAH7/Tyr, P) in mouse melanoma cells (B16F10) by Tat peptide (T) and an entrapment in elastic cationic niosomes (E) was described. The E composed of Tween 61/cholesterol/dodecyl dimethyl ammonium bromide at 1:1:0.5 molar ratio was pr...