Antibacterial compounds from zanthoxylum rhetsa

Antibacterial compounds from zanthoxylum rhetsa

A new amide, zanthorhetsamide (1), along with nine known compounds (2-10) was isolated from the roots and stem barks of Zanthoxylum rhetsa. The structure was characterized by spectroscopic methods. In addition, the antibacterial activity of the isolates was evaluated. Dihydrochelerythrine (4) exhibi...

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Bibliographic Details
Main Authors: Cholpisut Tantapakul, Wong Phakhodee, Thunwadee Ritthiwigrom, Kulsiri Yossathera, Suwanna Deachathai, Surat Laphookhieo
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84864933662&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51374
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Institution: Chiang Mai University
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Summary:A new amide, zanthorhetsamide (1), along with nine known compounds (2-10) was isolated from the roots and stem barks of Zanthoxylum rhetsa. The structure was characterized by spectroscopic methods. In addition, the antibacterial activity of the isolates was evaluated. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively.

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