Metabolites from the mangrove-derived fungus xylaria cubensis PSU-MA34

Metabolites from the mangrove-derived fungus xylaria cubensis PSU-MA34

Two new succinic acid derivatives, xylacinic acids A (1) and B (2), along with seven known compounds, including one succinic acid derivative (3), three mellein derivatives (4-6), cytochalasin D (7), 2-chloro-5-methoxy-3- methylcyclohexa-2,5-diene-1,4-dione (8) and isosclerone (9), were isolated from...

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Bibliographic Details
Main Authors: Saranyoo Klaiklay, Vatcharin Rukachaisirikul, Yaowapa Sukpondma, Souwalak Phongpaichit, Jirayu Buatong, Boonsom Bussaban
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84864951083&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51375
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Institution: Chiang Mai University
Description
Summary:Two new succinic acid derivatives, xylacinic acids A (1) and B (2), along with seven known compounds, including one succinic acid derivative (3), three mellein derivatives (4-6), cytochalasin D (7), 2-chloro-5-methoxy-3- methylcyclohexa-2,5-diene-1,4-dione (8) and isosclerone (9), were isolated from the mangrove-derived fungus Xylaria cubensis PSU-MA34. Their structures were established by spectroscopic evidence. They were evaluated for cytotoxicity against KB cells and antibacterial activity against Staphylococcus aureus ATCC 25923 and methicillin- resistant S. aureus.

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