PPARγ agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets

• المؤلفون الرئيسيون: Noppamas Pipatpiboon, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84455185141&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51416
• المؤسسة: Chiang Mai University

We previously demonstrated that a high-fat diet (HFD) consumption can cause not only peripheral insulin resistance, but also neuronal insulin resistance. Moreover, the consumption of an HFD has been shown to cause mitochondrial dysfunction in both the skeletal muscle and liver. Rosiglitazone, a pero...