Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study

This study examined the effects of a cognitive training program on cognitive function and neurochemistry changes in individuals with amnestic mild cognitive impairment (aMCI). Ten individuals with aMCI were randomly assigned to the experimental (n = 5) and control (n = 5) groups. The experimental gr...

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Main Authors: Sirinun Boripuntakul, Suchart Kothan, Pised Methapatara, Peeraya Munkhetvit, Somporn Sungkarat
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/51705
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-517052018-09-04T06:12:55Z Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study Sirinun Boripuntakul Suchart Kothan Pised Methapatara Peeraya Munkhetvit Somporn Sungkarat Health Professions Medicine Nursing This study examined the effects of a cognitive training program on cognitive function and neurochemistry changes in individuals with amnestic mild cognitive impairment (aMCI). Ten individuals with aMCI were randomly assigned to the experimental (n = 5) and control (n = 5) groups. The experimental group took part in an 18-session cognitive training program over a 6-week period. After completing the cognitive training course, the experimental group demonstrated significant improvement in memory, attention, and executive functions. With respect to the neurochemistry biomarkers, the myoinositol/creatine (mI/Cr) ratio was significantly decreased in the hippocampus, prefrontal cortex, and anterior cingulate cortex of the experimental group after training. Findings demonstrate that the cognitive training program showed promising evidence in improving cognitive functions in individuals with aMCI. The observed cognitive function improvement was accompanied by a decrease of mI levels. © 2012 by Informa Healthcare USA, Inc. 2018-09-04T06:06:41Z 2018-09-04T06:06:41Z 2012-06-01 Journal 15413152 02703181 2-s2.0-84861567944 10.3109/02703181.2012.657822 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861567944&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51705
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Health Professions
Medicine
Nursing
spellingShingle Health Professions
Medicine
Nursing
Sirinun Boripuntakul
Suchart Kothan
Pised Methapatara
Peeraya Munkhetvit
Somporn Sungkarat
Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
description This study examined the effects of a cognitive training program on cognitive function and neurochemistry changes in individuals with amnestic mild cognitive impairment (aMCI). Ten individuals with aMCI were randomly assigned to the experimental (n = 5) and control (n = 5) groups. The experimental group took part in an 18-session cognitive training program over a 6-week period. After completing the cognitive training course, the experimental group demonstrated significant improvement in memory, attention, and executive functions. With respect to the neurochemistry biomarkers, the myoinositol/creatine (mI/Cr) ratio was significantly decreased in the hippocampus, prefrontal cortex, and anterior cingulate cortex of the experimental group after training. Findings demonstrate that the cognitive training program showed promising evidence in improving cognitive functions in individuals with aMCI. The observed cognitive function improvement was accompanied by a decrease of mI levels. © 2012 by Informa Healthcare USA, Inc.
format Journal
author Sirinun Boripuntakul
Suchart Kothan
Pised Methapatara
Peeraya Munkhetvit
Somporn Sungkarat
author_facet Sirinun Boripuntakul
Suchart Kothan
Pised Methapatara
Peeraya Munkhetvit
Somporn Sungkarat
author_sort Sirinun Boripuntakul
title Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
title_short Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
title_full Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
title_fullStr Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
title_full_unstemmed Short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: A pilot study
title_sort short-term effects of cognitive training program for individuals with amnestic mild cognitive impairment: a pilot study
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861567944&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51705
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