Characterization and expression of cathepsin B2 in Fasciola gigantica

• Main Authors: Pathanin Chantree, Chaitip Wanichanon, Manussabhorn Phatsara, Krai Meemon, Prasert Sobhon
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866395887&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51717
• Institution: Chiang Mai University

Fasciola gigantica cathepsin B belongs to a family of cysteine proteases which is involved in invasion of host tissues. In this study, the recombinant cathepsin B2 (rFgCatB2), synthesized in Pichia pastoris, showed enzymatic activity on a fluorometric substrate Z-Phe-Arg-AMC and gelatin. Furthermore...