Developmental pharmacokinetic changes of lamivudine in infants and children

• Main Authors: Adriana H. Tremoulet, Mina Nikanjam, Tim R. Cressey, Kulkanya Chokephaibulkit, Ross McKinney, Mark Mirochnick, Edmund V. Capparelli
• Format: Journal
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868629145&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51832
• Institution: Chiang Mai University

Lamivudine is a nucleoside reverse transcriptase inhibitor widely used in infants and children in combination antiretroviral therapy to treat human immunodeficiency virus (HIV) infection. Developmental changes in lamivudine pharmacokinetic disposition were assessed by combining data from 7 studies o...