Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy

Objectives: To identify predisposing factors of fetal bradycardia following cordocentesis at mid-pregnancy and to compare the pregnancy outcomes to those without bradycardia. Methods: All cordocenteses performed at 1822 weeks of gestation were prospectively enrolled. The inclusion criteria consisted...

Full description

Saved in:
Bibliographic Details
Main Authors: Chanane Wanapirak, Wirawit Piyamongkol, Supatra Sirichotiyakul, Kasemsri Srisupundit, Theera Tongsong
Format: Journal
Published: 2018
Subjects:
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867493175&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51835
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-51835
record_format dspace
spelling th-cmuir.6653943832-518352018-09-04T06:10:03Z Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy Chanane Wanapirak Wirawit Piyamongkol Supatra Sirichotiyakul Kasemsri Srisupundit Theera Tongsong Medicine Objectives: To identify predisposing factors of fetal bradycardia following cordocentesis at mid-pregnancy and to compare the pregnancy outcomes to those without bradycardia. Methods: All cordocenteses performed at 1822 weeks of gestation were prospectively enrolled. The inclusion criteria consisted of: (i) singleton pregnancies; (ii) no fetal structural or chromosomal abnormalities; (iii) the procedures done by experienced operators. They were divided into two groups; procedures with fetal bradycardia (Group 1) and those without bradycardia (Group 2). Factors related to bradycardia were identified and pregnancy outcomes between the two groups were also compared. Results: Of 6147 cordocenteses recruited, 2829 met the inclusion criteria. Of these,152 had fetal bradycardia whereas the remaining 2677 did not. The procedures involving placenta penetration, and umbilical cord bleeding were significantly related to a higher rate of fetal bradycardia. On the other hand, cordocenteses with fetal bradycardia had a significantly higher rate of fetal loss (11.8 vs. 1.9%, respectively, p = 0.001) as well as a higher rate of low birth weight and preterm birth. Conclusions: Cordocentesis with placenta penetration and umbilical cord bleeding carries a higher risk for fetal bradycardia and fetal bradycardia was an independent factor for a higher rate of fetal loss, preterm birth and low birth weight. © 2012 Informa UK, Ltd. 2018-09-04T06:10:03Z 2018-09-04T06:10:03Z 2012-11-01 Journal 14764954 14767058 2-s2.0-84867493175 10.3109/14767058.2012.685787 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867493175&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51835
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Chanane Wanapirak
Wirawit Piyamongkol
Supatra Sirichotiyakul
Kasemsri Srisupundit
Theera Tongsong
Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
description Objectives: To identify predisposing factors of fetal bradycardia following cordocentesis at mid-pregnancy and to compare the pregnancy outcomes to those without bradycardia. Methods: All cordocenteses performed at 1822 weeks of gestation were prospectively enrolled. The inclusion criteria consisted of: (i) singleton pregnancies; (ii) no fetal structural or chromosomal abnormalities; (iii) the procedures done by experienced operators. They were divided into two groups; procedures with fetal bradycardia (Group 1) and those without bradycardia (Group 2). Factors related to bradycardia were identified and pregnancy outcomes between the two groups were also compared. Results: Of 6147 cordocenteses recruited, 2829 met the inclusion criteria. Of these,152 had fetal bradycardia whereas the remaining 2677 did not. The procedures involving placenta penetration, and umbilical cord bleeding were significantly related to a higher rate of fetal bradycardia. On the other hand, cordocenteses with fetal bradycardia had a significantly higher rate of fetal loss (11.8 vs. 1.9%, respectively, p = 0.001) as well as a higher rate of low birth weight and preterm birth. Conclusions: Cordocentesis with placenta penetration and umbilical cord bleeding carries a higher risk for fetal bradycardia and fetal bradycardia was an independent factor for a higher rate of fetal loss, preterm birth and low birth weight. © 2012 Informa UK, Ltd.
format Journal
author Chanane Wanapirak
Wirawit Piyamongkol
Supatra Sirichotiyakul
Kasemsri Srisupundit
Theera Tongsong
author_facet Chanane Wanapirak
Wirawit Piyamongkol
Supatra Sirichotiyakul
Kasemsri Srisupundit
Theera Tongsong
author_sort Chanane Wanapirak
title Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
title_short Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
title_full Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
title_fullStr Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
title_full_unstemmed Predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
title_sort predisposing factors and effects of fetal bradycardia following cordocentesis at mid-pregnancy
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867493175&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51835
_version_ 1681423841539129344