Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men

• Main Authors: Peter L. Anderson, David V. Glidden, Albert Liu, Susan Buchbinder, Javier R. Lama, Juan Vicente Guanira, Vanessa McMahan, Lane R. Bushman, Martín Casapía, Orlando Montoya-Herrera, Valdilea G. Veloso, Kenneth H. Mayer, Suwat Chariyalertsak, Mauro Schechter, Linda Gail Bekker, Esper Georges Kallás, Robert M. Grant
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866283847&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51846
• Institution: Chiang Mai University

Drug concentrations associated with protection from HIV-1 acquisition have not been determined. We evaluated drug concentrations among men who have sex with men in a substudy of the iPrEx trial (1). In this randomized placebo-controlled trial, daily oral doses of emtricitabine/tenofovir disoproxil f...