Screening for co-existence of α-thalassemia in β-thalassemia and in HbE heterozygotes via an enzyme-linked immunosorbent assay for Hb Bart's and embryonic ζ-globin chain

• Main Authors: Thanusak Tatu, Surakit Khuntarak, Surasit Suwannasin, Tiemjan Kiewkarnkha, Sakdinan Khamrin, Watchara Kasinrerk
• Format: Journal
• Published: 2018
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84862899879&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51919
• Institution: Chiang Mai University

We sought to demonstrate the ability of levels of Hb Bart's and ζ-globin chain quantified by enzymelinked immunosorbent assay (ELISA) in detecting α-thalassemia in β-thalassemia and HbE heterozygotes. We developed an in-house sandwich ELISA method using monoclonal antibodies (mAbs) to Hb Bart&#...