Timing of surgical closure of patent ductus arteriosus in preterm neonates?

A retrospective cohort study was conducted on 115 preterm neonates who underwent patent ductus arteriosus ligation after failure of medical treatment, at Chiang Mai University Hospital between January 2003 and December 2010. Two groups were defined: an early surgery group (39.1%) treated with surgic...

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Main Authors: Apichat Tantraworasin, Surin Woragidpoonpol, Supachai Chuaratanapong, Rekwan Sittiwangkul, Kaweesak Chittawatanarat
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/51938
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-519382018-09-04T06:12:03Z Timing of surgical closure of patent ductus arteriosus in preterm neonates? Apichat Tantraworasin Surin Woragidpoonpol Supachai Chuaratanapong Rekwan Sittiwangkul Kaweesak Chittawatanarat Medicine A retrospective cohort study was conducted on 115 preterm neonates who underwent patent ductus arteriosus ligation after failure of medical treatment, at Chiang Mai University Hospital between January 2003 and December 2010. Two groups were defined: an early surgery group (39.1%) treated with surgical closure within 21 days, and a late surgery group (60.9%) operated on >21 days after birth. There were significant differences between the 2 groups in terms of weight at surgery, birth weight, duration of intubation, ductal size, and preoperative indomethacin usage. The early surgery group had a longer intensive care unit stay, but differences in postoperative chronic lung disease, ductal size, and surfactant use were not significant. Babies with a low birth weight (<1,500 g) and those with a higher ductal gradient were more susceptible to chronic lung disease, but multivariate analysis showed no difference between early and late surgery patients in either early extubation or chronic lung disease. It was concluded that early patent ductus arteriosus ligation did not show more benefits than late surgery. © The Author(s) 2012. 2018-09-04T06:12:03Z 2018-09-04T06:12:03Z 2012-02-01 Journal 18165370 02184923 2-s2.0-84858247413 10.1177/0218492311430356 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84858247413&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51938
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Apichat Tantraworasin
Surin Woragidpoonpol
Supachai Chuaratanapong
Rekwan Sittiwangkul
Kaweesak Chittawatanarat
Timing of surgical closure of patent ductus arteriosus in preterm neonates?
description A retrospective cohort study was conducted on 115 preterm neonates who underwent patent ductus arteriosus ligation after failure of medical treatment, at Chiang Mai University Hospital between January 2003 and December 2010. Two groups were defined: an early surgery group (39.1%) treated with surgical closure within 21 days, and a late surgery group (60.9%) operated on >21 days after birth. There were significant differences between the 2 groups in terms of weight at surgery, birth weight, duration of intubation, ductal size, and preoperative indomethacin usage. The early surgery group had a longer intensive care unit stay, but differences in postoperative chronic lung disease, ductal size, and surfactant use were not significant. Babies with a low birth weight (<1,500 g) and those with a higher ductal gradient were more susceptible to chronic lung disease, but multivariate analysis showed no difference between early and late surgery patients in either early extubation or chronic lung disease. It was concluded that early patent ductus arteriosus ligation did not show more benefits than late surgery. © The Author(s) 2012.
format Journal
author Apichat Tantraworasin
Surin Woragidpoonpol
Supachai Chuaratanapong
Rekwan Sittiwangkul
Kaweesak Chittawatanarat
author_facet Apichat Tantraworasin
Surin Woragidpoonpol
Supachai Chuaratanapong
Rekwan Sittiwangkul
Kaweesak Chittawatanarat
author_sort Apichat Tantraworasin
title Timing of surgical closure of patent ductus arteriosus in preterm neonates?
title_short Timing of surgical closure of patent ductus arteriosus in preterm neonates?
title_full Timing of surgical closure of patent ductus arteriosus in preterm neonates?
title_fullStr Timing of surgical closure of patent ductus arteriosus in preterm neonates?
title_full_unstemmed Timing of surgical closure of patent ductus arteriosus in preterm neonates?
title_sort timing of surgical closure of patent ductus arteriosus in preterm neonates?
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84858247413&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51938
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