Enhancement of gene expression and melanin production of human tyrosinase gene loaded in elastic cationic niosomes

• Main Authors: Narinthorn Khositsuntiwong, Aranya Manosroi, Friedrich Götz, Rolf G. Werner, Worapaka Manosroi, Jiradej Manosroi
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84865863964&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/51975
• Institution: Chiang Mai University

Objectives Disturbance in the synthesis of tyrosinase might be one of the major causes of vitiligo. The enhancement of tyrosinase gene expression and melanin production by loading the plasmid in elastic cationic niosomes was investigated in tyrosinase gene knocked out human melanoma (M5) cells and i...