Improved SCFV ANTI-HIV-1 P17 binding affinity guided from the theoretical calculation of pairwise decomposition energies and Computational Alanine Scanning

Improved SCFV ANTI-HIV-1 P17 binding affinity guided from the theoretical calculation of pairwise decomposition energies and Computational Alanine Scanning

Computational approaches have been used to evaluate and define important residues for protein-protein interactions, especially antigen-antibody complexes. In our previous study, pairwise decomposition of residue interaction energies of single chain Fv with HIV-1 p17 epitope variants has indicated th...

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Bibliographic Details
Main Authors: Panthip Tue-Ngeun, Kanchanok Kodchakorn, Piyarat Nimmanpipug, Narin Lawan, Sawitree Nangola, Chatchai Tayapiwatana, Noorsaadah Abdul Rahman, Sharifuddin Md Zain, Vannajan Sanghiran Lee
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84888588591&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/52172
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84888588591&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/52172

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