Antiproliferative effect of alkaloids via cell cycle arrest from Pseuduvaria rugosa

• Main Authors: Orathai Uadkla, Supachai Yodkeeree, Mongkol Buayairaksa, Puttinan Meepowpan, Narong Nuntasaen, Pornngarm Limtrakul, Wilart Pompimon
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84873902938&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52268
• Institution: Chiang Mai University

Context: Pseuduvaria rugosa (Blume) Merr. (Annonacaea) grows widely in the south and southeast regions of Thailand. Preliminary screening for biological activities revealed that crude hexane, ethyl acetate, and acetone extracts from mixtures of leaves and twigs of P. rugosa showed cytotoxicity. Obje...