Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities

Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls (14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1′-hexenedione...

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Main Authors: Boonphong S., Puangsombat P., Baramee A., Mahidol C., Ruchirawat S., Kittakoop P.
格式: Article
語言:English
出版: 2014
在線閱讀:http://www.scopus.com/inward/record.url?eid=2-s2.0-34250746945&partnerID=40&md5=ee9eeff10c5609688d07b5d00fa8c832
http://www.ncbi.nlm.nih.gov/pubmed/17480099
http://cmuir.cmu.ac.th/handle/6653943832/5262
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機構: Chiang Mai University
語言: English
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總結:Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls (14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1′-hexenedione (10), and a new bibenzyl (11). Antimycobacterial, antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed. © 2007 American Chemical Society and American Society of Pharmacognosy.