Crystal structure of a thermostable lipase from Bacillus stearothermophilus P1

• Main Authors: Tyndall J.D.A., Sinchaikul S., Fothergill-Gilmore L.A., Taylor P., Walkinshaw M.D.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036431593&partnerID=40&md5=b9850f632e243f88a6a9cf5d397dc4f2; http://cmuir.cmu.ac.th/handle/6653943832/5279
• Institution: Chiang Mai University

We describe the first lipase structure from a thermophilic organism. It shares less than 20% amino acid sequence identity with other lipases for which there are crystal structures, and shows significant insertions compared with the typical α/β hydrolase canonical fold. The structure contains a zinc-...