Extraosseous osteosarcoma: A case report and review of the literature

Extraosseous osteosarcoma (EOO) is a rare soft tissue sarcoma that produces osteoid and bone. It is sometimes accompanied by cartilage. It is located in soft tissue without skeletal attachment. A previous study revealed that extraosseous osteosarcoma is a chemoresistant tumor with a poor prognosis a...

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Main Authors: Apiruk Sangsin, Nuttaya Pattamapaspong, Jongkolnee Settakorn, Taninnit Leerapun, Dumnoensun Pruksakorn
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/52867
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-528672018-09-04T09:33:47Z Extraosseous osteosarcoma: A case report and review of the literature Apiruk Sangsin Nuttaya Pattamapaspong Jongkolnee Settakorn Taninnit Leerapun Dumnoensun Pruksakorn Medicine Extraosseous osteosarcoma (EOO) is a rare soft tissue sarcoma that produces osteoid and bone. It is sometimes accompanied by cartilage. It is located in soft tissue without skeletal attachment. A previous study revealed that extraosseous osteosarcoma is a chemoresistant tumor with a poor prognosis and should be distinct from osseous osteosarcoma. Out of more than a hundred of osteosarcoma recorded during 1992 to 2012 in Chiang Mai Hospital, only one was EOO. This is a case report of a 44-year-old Asian man who first noticed a small right thigh soft tissue mass associated with pain. MRI reveals a heterogeneous mass in the quadriceps muscle without continuity with the bone. Wide resection of the tumor was performed. Microscopically, the tumors composed of large size spindle shape and bizarre malignant cell with osteoid production. After the resection, adjuvant radiation by brachytherapy technique, and chemotherapy was performed. At postoperative 24-months follow-up, the patient was free from local recurrence and distant metastasis, compared to seven months of median survival time for patients treated with resection alone in previous case reports. 2018-09-04T09:33:47Z 2018-09-04T09:33:47Z 2013-05-01 Journal 01252208 2-s2.0-84876760426 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876760426&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/52867
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Apiruk Sangsin
Nuttaya Pattamapaspong
Jongkolnee Settakorn
Taninnit Leerapun
Dumnoensun Pruksakorn
Extraosseous osteosarcoma: A case report and review of the literature
description Extraosseous osteosarcoma (EOO) is a rare soft tissue sarcoma that produces osteoid and bone. It is sometimes accompanied by cartilage. It is located in soft tissue without skeletal attachment. A previous study revealed that extraosseous osteosarcoma is a chemoresistant tumor with a poor prognosis and should be distinct from osseous osteosarcoma. Out of more than a hundred of osteosarcoma recorded during 1992 to 2012 in Chiang Mai Hospital, only one was EOO. This is a case report of a 44-year-old Asian man who first noticed a small right thigh soft tissue mass associated with pain. MRI reveals a heterogeneous mass in the quadriceps muscle without continuity with the bone. Wide resection of the tumor was performed. Microscopically, the tumors composed of large size spindle shape and bizarre malignant cell with osteoid production. After the resection, adjuvant radiation by brachytherapy technique, and chemotherapy was performed. At postoperative 24-months follow-up, the patient was free from local recurrence and distant metastasis, compared to seven months of median survival time for patients treated with resection alone in previous case reports.
format Journal
author Apiruk Sangsin
Nuttaya Pattamapaspong
Jongkolnee Settakorn
Taninnit Leerapun
Dumnoensun Pruksakorn
author_facet Apiruk Sangsin
Nuttaya Pattamapaspong
Jongkolnee Settakorn
Taninnit Leerapun
Dumnoensun Pruksakorn
author_sort Apiruk Sangsin
title Extraosseous osteosarcoma: A case report and review of the literature
title_short Extraosseous osteosarcoma: A case report and review of the literature
title_full Extraosseous osteosarcoma: A case report and review of the literature
title_fullStr Extraosseous osteosarcoma: A case report and review of the literature
title_full_unstemmed Extraosseous osteosarcoma: A case report and review of the literature
title_sort extraosseous osteosarcoma: a case report and review of the literature
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876760426&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/52867
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