Solid-to-solid peptide synthesis by glycyl endopeptidase

Glycyl endopeptidase catalysed solid-to-solid synthesis can be carried out efficiently for the model peptides Z-Gly-Phe-NH2, Z-Gly-Leu-NH2, Z-Gly-Tyr-NH2 and Z-Gly-Tyr-OEt. A small excess of acyl donor Z-Gly improved both the initial rate and final yield, whereas an excess of nucleophile Phe-NH2 pre...

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Bibliographic Details
Main Authors: Chaiwut P., Kanasawud P., Halling P.J.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-33847354740&partnerID=40&md5=1b453bb0533cd4b2c1995bb73895a28a
http://cmuir.cmu.ac.th/handle/6653943832/5291
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Institution: Chiang Mai University
Language: English